While NBC hasn't released its full schedule as of yet, they did announce that one show in particular will definitely not be returning. According to Entertainment Weekly, NBC has cancelled the series Life.
The show also reported that another series on the cancellation bubble, Chuck, might move to a different date if it is in fact renewed. The network indicated that they wanted to pair Heroes with a new series on Monday nights, so Chuck might be moved to another night, if it is picked up for a third season.
The network also indicated that they would continue the series Law & Order: Special Victims Unit with or without stars Christopher Meloni and Mariska Hargitay. Negotiations to bring the stars back to the series are ongoing, but it seems the show would move on in their absence, if a deal is not met.