Neil Flynn (Scrubs) will star opposite Patricia Heaton in ABC's comedy pilot The Middle, while Amy Gumenick has been set in the lead role of Lifetime Movie Network's telefilm The Natalee Holloway Story, according to The Hollywood Reporter.

The WBTV-produced The Middle revolves around a middle-class couple (Heaton and Flynn) in middle America who cope with the financial and emotional strain of trying to raise three kids.

The Natalee Holloway Story, which will be directed by Mikael Salomon, is based on the book "Loving Natalee: A Mother's Testament of Hope and Faith" by Holloway's mother, Beth Twitty, and chronicles Twitty's (Tracy Pollan) efforts to discover the truth about what happened to her daughter (Gumenick), who disappeared in 2005 during a senior class vacation in Aruba.