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Beginning almost immediately after the first one, Brigitte is now on the run from her quiet suburb of Bailey Downs, and on the way she tries to prevent what happened to her sister from happening to her by shooting up with monkshood. Eventually she collapses, however, and the police that pick her up assume the monkshood is a drug, so off to rehab she goes.
Once inside, she is deprived of the only thing that will stop her from turning into a beast and killing everyone and everything in her way. That's a problem. She meets a girl who is quiet and not well-liked, much like herself, by the name of Ghost that helps her deal with her new problem and try to escape the curse.