The story centers on Barrett (Olivia Wilde), a woman riddled with anxiety, who meets and falls for the agoraphobic George (Jason Sudeikis). Because of both their phobias, Barrett and George spend most of their time speaking on the phone, until they finally decide to conquer their fears and be with one another. Brie Larson will play Barrett's sister, and Fred Armisen will play George's friend, the only person he has contact with from the outside world.
Christopher Storer will make his directorial debut with Relanxious, working from his own screenplay. Daniel Dubiecki (Ceremony) and Lorene Scafaria (Seeking a Friend for the End of the World) will produce. Shooting is scheduled to begin sometime this summer in Chicago.