Michael Shamberg and Stacey Sher (Along Came Polly) have closed development deals for projects involving Keanu Reeves and Harrison Ford. The Reeves project is a comedy based on an idea generated by the "Matrix" star. He'll play an American who becomes a success in London and has to deal with the cultural differences.

They've set Michael Kalesniko to script the pic.

The Ford project is a medical drama drawn from "For His Sick Kid," a Geeta Anand book the studio just acquired, about a man who finances a cure for a rare disease that is killing two of his kids -- then has to fight to get them access to the drug. Judith Regan will publish the book.

The producers worked with Ford developing "A Walk Among the Tombstones," a project from which Ford ultimately walked away. Shamberg said that they'd agreed to try to work together again, and he and Sher approached Ford with "For His Sick Kid," a tale that originally appeared as an article in the Wall Street Journal.

Shamberg and Sher just closed rights deals for the project and are looking to secure a writer.