Rachel Weisz and Toni Collette have signed on to star in the drama Miss You Already, which Catherine Hardwicke is directing. We first reported on this project back in February 2012, when Jennifer Aniston was attached to star and Paul Andrew Williams was set to direct.

The story follows two lifelong friends (Rachel Weisz and Toni Collette) in London whose relationship becomes fractured when one becomes pregnant and the other suddenly falls ill.

RELATED: Miss You Already Trailer Starring Drew Barrymore & Toni Collette

Morwenna Banks wrote the screenplay, with Embargo Films' Christopher Simon and Felix Vossen producing. Production is scheduled to begin this September in the U.K.

Here's what Catherine Hardwicke had to say about Morwenna Banks' script.

"When I met Morwenna Banks and read her script, I really felt her passion for this story - this is something she lived through. She managed to take real life and turn it into a powerful, laugh-and-cry-out-loud screenplay."

Rachel Weisz most recently starred in Oz: The Great and Powerful, and Toni Collette stars in the upcoming indie Lucky Them.