A mini Cheers reunion is brewing at ABC, as Rhea Perlman has joined the cast of Kirstie Alley's multi-camera comedy pilot The Manzanis.

Kirstie Alley stars in the show as Angela Manzani, the head of an Italian American household who moves into the New Jersey suburbs and instantly begins to clash with her uptight neighbors. Rhea Perlman will play Angela's live-in mother-in-law Camille Manzani.

This will only be the second time the two actress have worked together since Cheers concluded in May of 1993. Rhea appeared as herself on Kirstie Alley's reality series Fat Actress in 2005.