Rob Lowe and Kaley Cuoco have joined Lifetime's TV movie The Drew Peterson Story.

Rob Lowe will play Drew Peterson, a charismatic, womanizing Chicago police officer that was charged with the death of his third wife after the mysterious disappearance of his fourth wife.

The Big Bang Theory co-star Kaley Cuoco will play Peterson's fourth wife, Stacy, whose disappearance put the spotlight on him.

The Drew Peterson Story is based on Joseph Hosey's nonfiction book "Fatal Vows: The Tragic Wives of Drew Peterson".

After following up on tips from a neighbor, authorities arrested Peterson and indited him for the death of his previous wife, Kathleen, who in 2004 was found drowned in an empty bathtub. Peterson has denied involvement in both cases and is awaiting trial.

No production date has been set.