Rooney Mara has taken the lead role in director Steven Soderbergh's Side Effects.

This thriller revolves around a young woman that gets hooked on prescription drugs out of fear of her husband and his imminent release from prison. The actress will replace Blake Lively, who recently dropped out of the project. Channing Tatum is still set to co-star.

Scott Z. Burns wrote the screenplay. The film will be released by Open Road. Shooting is scheduled to begin this April.