Last week, the first trailer debuted for Upstream Color, writer-director Shane Carruth's long-awaited follow-up to his critically-acclaimed 2004 debut Primer. Today, we have the second trailer for this bizarre thriller, starring Andrew Sensenig and Amy Seimetz as a couple trapped within the life cycle of a mysterious, ageless, organism. The film will make its world premiere at the Sundance Film Festival next month, before opening in theaters March 22, 2013. Until then, you can feast on this strange footage.