The Untitled Spider-Man Reboot is currently shooting in the Los Angeles area, and it just wouldn't be a Marvel movie if there wasn't a cameo from Stan Lee. The Spider-Man creator confirmed he will have a cameo appearance in the Untitled Spider-Man Reboot and you can read the early details below:

My pal Avi Arad, producer of the new Spider-Man, called to tell me how excited he is about the film. Then came the surprise-- Avi told me my cameo is all set for Spidey 4, and when he described it, I realized it's the best, most unusual one yet!"
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While he wouldn't say any specific details on his role, it seems we'll get to see Stan Lee in an action scene this time around:

I wish I could tell you what my cameo is, but that would kill the surprise. But I'll tell you this much-I'm finally in an action scene!"