It seems that a hit CW series is poking a little fun at its competitors... which could pave the way for a return of a popular actor. Entertainment Weekly's Ausiello Files has posted an image of Supernatural's Sam (Jared Padalecki) and Dean (Jensen Ackles) in a Seattle Grace-like hospital, in a nod to Grey's Anatomy. Click below to see this interesting image of the Winchester brothers.

Sam and Dean Spoof Grey's Anatomy

The episode, appropriately dubbed Changing Channels, will air on November 5 and will also feature nods to the hit ABC drama CSI as well, according to the site.

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The site also left a cryptic hint about a nod to Grey's Anatomy that Supernatural fans, "will find particularly amusing." Could this be a clue that we will see Jeffrey Dean Morgan return in a guest-starring role? We'll have to wait until Thursday, November 5 at 9 PM ET on the CW Network to find out.