Another Memorial Day weekend has come and gone, as 20th Century Fox's X-Men: Apocalypse pulls away with an easy win at the box office. The superhero sequel took in $65.3 million over the three-day weekend and $80 million over the four-day holiday. This superhero adventure's reign at the top may be over quickly, though, with three newcomers hitting theaters this Friday, including Paramount's Teenage Mutant Ninja Turtles: Out of the Shadows, Warner Bros.' Me Before You and Universal's Popstar: Never Stop Never Stopping arriving in wide release. If our projections are accurate, Ninja Turtles 2 should be the king of them all.

According to Box Office Mojo, Teenage Mutant Ninja Turtles: Out of the Shadows will easily have the widest release this weekend, opening in an estimated 3,800 theaters. Me Before You is slated to open in more than 2,500 theaters, while Popstar is set to open in approximately 2,200 theaters. Me Before You currently sits at a 55% rating on Rotten Tomatoes, although there aren't enough reviews in for Teenage Mutant Ninja Turtles: Out of the Shadows and Popstar. We're predicting that Teenage Mutant Ninja Turtles: Out of the Shadows should easily take the top spot with $61.3 million, which, if true, would come in just under its predecessor, 2014's Teenage Mutant Ninja Turtles, which opened with $65.5 million two summers ago. But there is a chance that it could be much bigger than that.

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After super villain Shredder escapes custody, he joins forces with mad scientist Baxter Stockman (Tyler Perry) and two dimwitted henchmen, Bebop and Rocksteady, to unleash a diabolical plan to take over the world. As the Turtles prepare to take on Shredder and his new crew, they find themselves facing an even greater evil with similar intentions: The notorious Krang. Original Teenage Mutant Ninja Turtles stars Alan Ritchson (Raphael), Noel Fisher (Michelangelo), Pete Ploszek (Leonardo) and Jeremy Howard (Donatello) all return to reprise their roles as the Turtles, along with Megan Fox (April O'Neill) and Will Arnett (Vern Fenwick). Tyler Perry has come aboard to play Baxter Stockman, alongside Stephen Amell as Casey Jones, Brian Tee as Shredder and Brittany Ishibashi as Karai. Laura Linney also joins the cast as a law enforcement officer.

X-Men: Apocalypse will likely drop to second place with $30.4 million, followed by newcomer Me Before You in third with $15.1 million. Me Before You follows Louisa "Lou" Clark (Emilia Clarke), who lives in a quaint town in the English countryside. With no clear direction in her life, the quirky and creative 26-year-old goes from one job to the next in order to help her tight-knit family make ends meet. Her normally cheery outlook is put to the test, however, when she faces her newest career challenge. Taking a job at the local "castle," she becomes caregiver and companion to Will Traynor (Sam Claflin), a wealthy young banker who became wheelchair bound in an accident two years prior, and whose whole world changed dramatically in the blink of an eye. No longer the adventurous soul he once was, the now cynical Will has all but given up. That is until Lou determines to show him that life is worth living. Embarking together on a series of adventures, both Lou and Will get more than they bargained for, and find their lives-and hearts-changing in ways neither one could have imagined.

Alice Through the Looking Glass will most likely drop to fourth place with a predicted $12.3 million, with Popstar rounding out the top 5 with $10.2 million. Universal Pictures' Popstar: Never Stop Never Stopping is headlined by musical digital-shorts superstars Andy Samberg, Akiva Schaffer and Jorma Taccone, collectively known as The Lonely Island. The comedy goes behind the scenes as singer/rapper Conner4Real (Andy Samberg) faces a crisis of popularity after his sophomore album flops, leaving his fans, sycophants and rivals all wondering what to do when he's no longer the dopest star of all.

The latest comedy from blockbuster producer Judd Apatow (Trainwreck, Superbad) co-stars Sarah Silverman, Tim Meadows and Maya Rudolph and many of the biggest names in comedy and music in cameo performances. Co-directed by Akiva Schaffer and Jorma Taccone and written by The Lonely Island trio, Popstar is also produced by Rodney Rothman (producer of Get Him to the Greek, Forgetting Sarah Marshall; co-writer of 22 Jump Street), as well as Andy Samberg, Akiva Schaffer and Jorma Taccone.

The top 10 will be rounded out by The Angry Birds Movie ($9.1 million), Captain America: Civil War ($8.7 million), Neighbors 2: Sorority Rising ($5.2 million), The Jungle Book ($3.4 million) and The Nice Guys ($3 million). Also opening this week in limited release is Independent's sci-fi thriller Approaching The Unknown, United Entertainment Partners' drama The Final Master, Oscilloscope Pictures' drama The Fits, Abramorama's documentary Time to Choose and FilmRise's documentary The Witness. It isn't known quite yet if any of these limited release movies will expand in the weeks to come.

Looking ahead to next weekend, three new movies will debut in wide release, two of which are sequels. Universal will debut their long-awaited video game adaptation Warcraft, which will go up against Warner Bros.' horror sequel The Conjuring 2 and Lionsgate's Now You See Me 2. Be sure to check back on Sunday for the box office estimates, and again next Tuesday for the latest round of predictions. Until then, check out the projected top 10 for the weekend of June 3.