The film follows England's Queen Elizabeth II in the wake of Princess Diana's untimely death in a 1997 Paris car crash. Frears was named best director and The Queen screenwriter won for best screenplay.
Helen Mirren won for best actress for her performance as the queen and Michael Sheen was named best supporting actor for his portrayal of Prime Minister Tony Blair.
Forest Whitaker won for best actor for his chilling portrayal of Ugandan dictator Idi Amin in The Last King of Scotland.
The quirky family comedy Little Miss Sunshine -- starring Abigail Breslin, Steve Carell, Toni Collette, Greg Kinnear and Alan Arkin -- won the for best ensemble cast. Its directors, Jonathan Dayton and Valerie Faris, won for best director debut.
The NYFCO's 26 members also honored Philip Glass for his score and Dick Pope for cinematography for The Illusionist.