The movie would reunite the 2 stars as brothers Julius and Vincent, conceived experimentally, who discover they have third sibling. The twist in the story is that Eddie Murphy would play the sibling.
The film is still seeking it's director, but Ivan Reitman will be attached to produce with Joe Medjuk, Tom Pollock and Ali Bell.
Related: Twins Sequel Triplets Gets Delayed
We went one-on-one with actor Danny DeVito to talk about the possibility of the Twins sequel at Comic-Con 2011. Check out what he had to say last summer about the project...