Prime: According to The Hollywood Reporter, as Prime started production Wednesday, Uma Thurman has taken over the leading role following Sandra Bullock's departure from the project. And Annie Parisse has joined the cast to play Katherine, the best buddy of Thurman's character.

Thurman entered the picture late last month after Bullock withdrew over issues regarding script approval. Thurman plays a woman who falls in love with the son (Bryan Greenberg) of her therapist (Meryl Streep).

Ben Younger is directing from his own script.