According to Variety, Vera Farmiga will play the female lead opposite Matt Damon, Leonardo DiCaprio and Jack Nicholson in Martin Scorsese's "The Departed" for Warner Bros.

At the same time, she has closed a deal for a supporting role in Anthony Minghella's Breaking and Entering, starring Jude Law.

Farmiga, who was honored by the 2004 Sundance Film Festival for her performance in Down to the Bone, followed with a role as Liev Schreiber's love interest in The Manchurian Candidate and a part in the ensemble of HBO's "Iron Jawed Angels."

She will next be seen starring opposite Paul Walker in Running Scared, a drama directed by Wayne Kramer (The Cooler).