According to The Hollywood Reporter, Vince Vaughn is set to star in an untitled David O. Russell-directed and -written comedy for Universal Pictures. Studio-based Mandalay Pictures, Gregory Goodman and Russell are producing.

Vaughn will play the wiseass host of a radio call-in show he runs with his producer girlfriend. His life is turned upside down when he starts taking on the qualities of his neurotic callers.

Russell wrote the current draft of the screenplay, which is based on a screenplay by David Cohen and Tony Lord. An early fall start date is being eyed. As opposed to some of Russell's more quirky and independent fare, the movie is designed to be a big, commercial comedy with his sensibilities, Russell said.