When Stewie gets upset with Lois for leaving him at home in the , he vows to carry out a diabolical plan in the "Stewie Kills Lois," the 100th episode of Family Guy, airing November 4th after The Simpsons Treehouse of Horror XVIII! Watch our clips below.

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Simon Cowell and Randy Jackson Interview

Paula Abdul Interview

Seth Green Interview

Adam West Interview

Alex Borstein Interview

Mila Kunis Interview

Seth MacFarlane Interview

Mike Henry Interview

The 100th episode, "Stewie Kills Lois," airs Sunday November 4th at 8:30 PM ET/PT on Fox.

Dont't forget to also check out: Family Guy

B. Alan Orange at Movieweb
B. Alan Orange