When four ruthless, powerful Villains “Knox” (guest star Jaime Hector), Flint (guest star Blake Shields), The German (guest star Ken Lally) and Jesse (guest star Francis Capra) -- bust into a bank and take hostages, Angela (Cristine Rose) sends H.R.G. (Jack Coleman) and his shocking, new empowered partner in after them.
Determined to derail a cataclysmic future, Peter (Milo Ventimiglia) must first find what he lost along the way.
Meanwhile, Hiro (Masi Oka) and Ando (James Kyson Lee) track Daphne (guest star Brea Grant) and part of “the formula” to Germany, but run afoul of The Haitian (guest star Jimmy Jean-Louis). Horrified by her ability, Tracy Strauss (Ali Larter) leaves Washington, D.C. to search for answers about Niki.
A distraught Claire (Hayden Panettiere) asks Meredith (guest star Jessalyn Gilsig) to teach her how to fight. As his romance with Maya (Dania Ramirez) intensifies, Suresh (Sendhil Ramamurthy) finds himself unprepared when his experiment yields some unexpected results.
Adrian Pasdar, Greg Grunberg and Zachary Quinto star. Randall Bentley, Ashley Crow, Noah Gray-Cabey, Ronald Guttman and Ntare Mwine guest star.