Watch the Pilot episode of Showtime's latest show, The Big C, right now in the players below!

Emmy nominee Oliver Platt (Huff, Frost/Nixon) stars as her immature, yet well-meaning husband, and Oscar nominee Gabourey Sidibe (Precious) plays her precocious student. Weeds viewers, still stunned by the last year's season finale, will finally learn what will become of the Botwins after Shane (Alexander Gould) clubbed Pilar (Kate del Castillo) to death.

After being diagnosed with melanoma, Cathy decides to build a pool in her backyard, much to the chagrin of her older curmudgeonly neighbor, Marlene. Cathy's son, Adam, plays pranks on her while her husband Paul tries to get back in her good graces. After trying to reconnect with her willfully homeless brother Sean, Cathy devises a weight-loss plan for Andrea, one of her summer school students.

Brian B.