Winona Ryder has signed on star in the Ron Howard comedy Cheaters, reports Deadline.

Winona Ryder will play Kevin James' wife.

The film tells of a man (Vince Vaughn) who spots his best friend's (James) wife (Ryder) with another man, and must decide whether or not to tell his pal.

Howard is directing from a script by Wall Street: Money Never Sleeps scribe Allan Loeb.

No production date has been set.