While many weren't too familiar with ALS (a.k.a. Lou Gehrig's Disease) before this summer, the hundreds of Ice Bucket Challenge videos helped spread awareness of this degenerative disease. Today, we have the first trailer for You're Not You, which stars Hilary Swank as Kate, a pianist who becomes stricken with ALS.

Based on Michelle Wildgen's book, this drama follows Kate and her husband (Josh Duhamel) as they find the most unorthodox caretaker in young college student Bec (Emmy Rossum) as they both change each other's lives. Take a look at the first footage, along with two new photos from director George C. Wolfe's adaptation, co-starring Loretta Devine, Ali Larter, Jason Ritter and Marcia Gay Harden, arriving in theaters and VOD platforms October 10.

Academy Award winner Hilary Swank (Conviction, Million Dollar Baby) and rapidly rising star Emmy Rossum (Shameless) intertwine in You're Not You, a surprisingly funny, defiantly unsentimental and starkly moving portrait of a high-stakes friendship between two women - one literally in need of a voice, the other discovering the full power of hers.

Kate (Swank) is a suave, successful classical pianist just diagnosed with ALS (commonly known as Lou Gehrig's Disease). Bec (Rossum) is a brash college student and would-be rock singer who can barely keep her wildly chaotic affairs, romantic and otherwise, together. Yet, when Bec takes a job assisting Kate, just as Kate's marriage to Evan (Josh Duhamel) hits the skids, both women come to rely on what becomes an unconventional, sometimes confrontational and fiercely honest bond. As meticulous, willful Kate begins to rub off on whirlwind, spontaneous Bec - and vice versa - both women find themselves facing down regrets, exploring new territory and expanding their ideas of who they want to be.

<strong><em>You're Not You</em></strong> photo 1
<strong><em>You're Not You</em></strong> photo 2